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Clostridium histolyticum : ウィキペディア英語版 | Clostridium histolyticum
''Clostridium histolyticum'' is a species of bacteria found in feces and the soil. It is a motile, gram-positive, facultative anaerobe. ''C. histolyticum'' is pathogenic in many species, including guinea pigs, mice, and rabbits, and humans. ''C. histolyticum'' has been shown to cause gas gangrene, often in association with other bacteria species. ==History== In 1916, Weinberg and Séguin isolated this bacterium from patients with gas gangrene and called it ''Bacillus histolyticus''. They discovered this bacteria was pathogenic for guinea pigs, mice, and rabbits, but less so for rats. Intramuscular injection of culture caused extensive local tissue destruction, extrusion of a hemorrhagic muscle pulp, splitting of the skin, denudation of the bone, and sometimes autoamputation. In 1922, Heller renamed the bacterium ''Weinbergillus histolyticus'', and a year later Bergey, Harrison, et al. reclassified it as ''Clostridium histolyticum''.
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